Leupeptin
Product Specifications
CAS Number
24365-47-7
Target
Virus Protease, Cysteine Protease, Serine Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Bioactivity
Leupeptin is a competitive protease inhibitor produced by actinomycetes. Leupeptin can inhibit cysteine, serine and threonine peptidases. Leupeptin inhibits serine proteinases (trypsin (Ki=3.5 nM), plasmin (Ki= 3.4 nM), porcine kallikrein), and cysteine proteinases (papain, cathepsin B (Ki = 4.1 nM), endoproteinase Lys-C) . Leupeptin does not inhibit α-chymotrypsin or thrombin.
Smiles
CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)NC(CCCNC(N)=N)C=O
Molecular Formula
C20H38N6O4
Molecular Weight
426.562
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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