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Bisindolylmaleimide I

Product Specifications

CAS Number

133052-90-1

Target

GSK-3, PDGFR, PKC

Related Pathways

Stem Cells, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

Purity

0.9908

Bioactivity

Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor, exhibiting a Ki of 14 nM.

Smiles

CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c2ccccc12

Molecular Formula

C25H24N4O2

Molecular Weight

412.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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