GDC-0349
Product Specifications
CAS Number
1207360-89-1
Target
PI3K, Autophagy, mTOR
Related Pathways
Autophagy, PI3K/Akt/mTOR signaling
Purity
0.9898
Bioactivity
GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
Smiles
CCNC(=O)Nc1ccc(cc1)-c1nc2CN(CCc2c(n1)N1CCOC[C@@H]1C)C1COC1
Molecular Formula
C24H32N6O3
Molecular Weight
452.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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