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Droxinostat

Product Specifications

CAS Number

99873-43-5

Target

Apoptosis, HDAC

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic, Apoptosis

Purity

0.9983

Bioactivity

Droxinostat (NS 41080) is a selective HDAC inhibitor, primarily targeting HDACs 6 and 8 with IC50 values of 2.47 μM and 1.46 μM, respectively. It is over 8-fold more selective against HDAC3 and shows no inhibition for HDAC1, 2, 4, 5, 7, 9, and 10.

Smiles

Cc1cc(Cl)ccc1OCCCC(=O)NO

Molecular Formula

C11H14ClNO3

Molecular Weight

243.69

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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