Droxinostat
Product Specifications
CAS Number
99873-43-5
Target
Apoptosis, HDAC
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic, Apoptosis
Purity
0.9983
Bioactivity
Droxinostat (NS 41080) is a selective HDAC inhibitor, primarily targeting HDACs 6 and 8 with IC50 values of 2.47 μM and 1.46 μM, respectively. It is over 8-fold more selective against HDAC3 and shows no inhibition for HDAC1, 2, 4, 5, 7, 9, and 10.
Smiles
Cc1cc(Cl)ccc1OCCCC(=O)NO
Molecular Formula
C11H14ClNO3
Molecular Weight
243.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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