What is the catalog number for Clevudine?

The catalog number for Clevudine is T6446.

What sizes are available for Clevudine?

Clevudine is available in the following size(s): 25 mg, 50 mg, 1 mL - 10 mM (in DMSO), 100 mg.

How many pack sizes does Clevudine come in?

Clevudine is available in 4 different pack sizes.

Is Clevudine in stock?

Clevudine is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Clevudine?

Clevudine is manufactured by Molfinity.

What is the estimated delivery time for Clevudine?

Estimated delivery time for Clevudine is approximately 10 business day(s), depending on your location.

Clevudine

Product Specifications

CAS Number

163252-36-6

Target

Virus Protease, DNA/RNA Synthesis, HBV

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Microbiology/Virology

Purity

0.9998

Bioactivity

Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV) . Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase) . Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA), therefore the patient is less likely to have a relapse after treatment is discontinued.