4-tert-Octylphenol
Product Specifications
CAS Number
140-66-9
Target
DNA/RNA Synthesis, Endogenous Metabolite, Apoptosis
Related Pathways
Metabolism, Apoptosis, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.9979
Bioactivity
4-tert-Octylphenol, an endocrine-disrupting chemical with estrogenic properties, notably induces apoptosis in offspring mouse brain neuronal progenitor cells. This compound decreases levels of bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), thereby diminishing the proliferation of neuronal progenitors. Consequently, 4-tert-Octylphenol adversely affects brain development and behavior in mice.
Smiles
CC(C)(C)CC(C)(C)C1=CC=C(O)C=C1
Molecular Formula
C14H22O
Molecular Weight
206.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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