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CCT129202

Product Specifications

CAS Number

942947-93-5

Target

Aurora Kinase

Related Pathways

Cell Cycle/Checkpoint|||Chromatin/Epigenetic

Purity

0.9814

Bioactivity

CCT129202 is an ATP-competitive pan-Aurora inhibitor for Aurora A, Aurora B and Aurora C with IC50 of 0.042 ?M, 0.198 ?M and 0.227 ?M, respectively. It is less potent to FGFR3, GSK3?, PDGFR?, etc.

Smiles

CN(C)c1ccc(cc1)-c1nc2c(N3CCN(CC(=O)Nc4nccs4)CC3)c(Cl)cnc2[nH]1

Molecular Formula

C23H25ClN8OS

Molecular Weight

497.02

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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