AKI603
Product Specifications
CAS Number
1432515-73-5
Target
Aurora Kinase
Related Pathways
Cell Cycle/Checkpoint, Chromatin/Epigenetic
Purity
0.9981
Bioactivity
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA) (IC50 = 12.3 nM) . AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].
Smiles
CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(cc2)[N+]([O-])=O)n1
Molecular Formula
C19H23N9O2
Molecular Weight
409.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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