Talotrexin ammonium
Product Specifications
CAS Number
648420-92-2
Target
DHFR|||Others|||Antifolate
Related Pathways
Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Others|||Metabolism
Purity
0.9757
Bioactivity
Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, helping to inhibit tumor growth.
Smiles
NC=1C2=C(N=CC(CNC3=CC=C(C(N[C@@H](CCCNC(=O)C4=C(C(O)=O)C=CC=C4)C(O)=O)=O)C=C3)=N2)N=C(N)N1.N
Molecular Formula
C27H30N10O6
Molecular Weight
590.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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