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Talotrexin ammonium

Product Specifications

CAS Number

648420-92-2

Target

DHFR|||Others|||Antifolate

Related Pathways

Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Others|||Metabolism

Purity

0.9757

Bioactivity

Talotrexin ammonium is a non-polyglutamic acid antifolate. Talotrexin ammonium inhibits tumor growth by targeting dihydrofolate reductase (DHFR), thereby improving anti-tumor activity in a wide range of cancer models, helping to inhibit tumor growth.

Smiles

NC=1C2=C(N=CC(CNC3=CC=C(C(N[C@@H](CCCNC(=O)C4=C(C(O)=O)C=CC=C4)C(O)=O)=O)C=C3)=N2)N=C(N)N1.N

Molecular Formula

C27H30N10O6

Molecular Weight

590.59

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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