Butein
Product Specifications
CAS Number
487-52-5
Target
EGFR, Autophagy, Apoptosis, PDE
Related Pathways
Apoptosis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Metabolism, Autophagy, Angiogenesis
Purity
>99.99%
Bioactivity
Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator. It sensitizes HeLa cells to Cisplatin by targeting FoxO3a via the AKT and ERK/p38 MAPK pathways.
Smiles
Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1
Molecular Formula
C15H12O5
Molecular Weight
272.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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