Butein

Product Specifications

CAS Number

487-52-5

Target

EGFR|||Autophagy|||Apoptosis|||PDE

Related Pathways

Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Metabolism|||Autophagy|||Angiogenesis

Purity

>99.99%

Bioactivity

Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator. It sensitizes HeLa cells to Cisplatin by targeting FoxO3a via the AKT and ERK/p38 MAPK pathways.

Smiles

Oc1ccc(C(=O)\C=C\c2ccc(O)c(O)c2)c(O)c1

Molecular Formula

C15H12O5

Molecular Weight

272.25

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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