What is the catalog number for JAK1/TYK2-IN-3?

The catalog number for JAK1/TYK2-IN-3 is T64265.

What sizes are available for JAK1/TYK2-IN-3?

JAK1/TYK2-IN-3 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does JAK1/TYK2-IN-3 come in?

JAK1/TYK2-IN-3 is available in 3 different pack sizes.

Is JAK1/TYK2-IN-3 in stock?

JAK1/TYK2-IN-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures JAK1/TYK2-IN-3?

JAK1/TYK2-IN-3 is manufactured by Molfinity.

What is the estimated delivery time for JAK1/TYK2-IN-3?

Estimated delivery time for JAK1/TYK2-IN-3 is approximately 10 business day(s), depending on your location.

JAK1/TYK2-IN-3

Product Specifications

Target

Others, JAK

Related Pathways

Angiogenesis, Others, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, JAK/STAT signaling

Bioactivity

JAK1/TYK2-IN-3 is a selective, potent, orally active dual inhibitor of TYK2 (IC50: 6 nM) and JAK1 (IC50: 37 nM), with selective action on JAK2 (IC50: 140 nM) and JAK3 (IC50: 362 nM) . It regulates the expression of TYK2/JAK1-related genes and formation of Th1, Th2, and Th17 cells to exert anti-inflammatory activity.