HDAC/HSP90-IN-4
Product Specifications
Target
Others|||HSP|||HDAC
Related Pathways
Cytoskeletal Signaling|||Metabolism|||DNA Damage/DNA Repair|||Others|||Chromatin/Epigenetic
Bioactivity
HDAC/HSP90-IN-4 significantly inhibited HDAC and HSP90 activity, with compound 20 (HDACIC50= 194 nM; HSP90?IC50= 153 nM) and compound 26 ((HDACIC50= 360 nM; HSP90?IC50= 77 nM) having the strongest HDAC and HSP90? inhibition. effect. Both compounds induced HSP90 expression and down-regulated HSP90 client proteins, which play an important role in the regulation of cancer cell survival and invasion.
Molecular Formula
C20H23N3O6
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
abx029343-01 80 µL
Potassium Voltage-Gated Channel Subfamily A Member 6 (KCNA6) Antibody
Ask
View Details 
abx029343-02 400 µL
Potassium Voltage-Gated Channel Subfamily A Member 6 (KCNA6) Antibody
Ask
View Details GTR15160997 1 Vial
Lentiviral human S100A13 shRNA (UAS) - Lentiviral human S100A13 shRNA (UAS) (25)
Ask
View Details