EGFR-IN-48
Product Specifications
Target
Others, EGFR
Related Pathways
Angiogenesis, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-48 is a potent, orally active EGFR inhibitor that acts on EGFRd19/TM/CS (IC50: 0.193 nM), EGFRLR/TM/CS (IC50: 0.251 nM), EGFRWT (IC50: 10.4 nM) . EGFR-IN-48 is also able to inhibit EGFR-IN-48 also inhibits the proliferation of BaF3EGFR del19/T790M/C797S cells (IC50: 1.526 nM) and PC-9EGFR del19/T790M/C797S cells (IC50: 66.7 nM) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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