EGFR/HER2-IN-5
Product Specifications
Target
Others, EGFR
Related Pathways
Others, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
EGFR/HER2-IN-5 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM) . EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits significant anti-tumour effects in vivo and can be used to study lung cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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