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EGFR/HER2-IN-5

Product Specifications

Target

Others, EGFR

Related Pathways

Others, Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

Bioactivity

EGFR/HER2-IN-5 is an irreversible, orally active dual inhibitor of EGFR activity (IC50: 0.6 nM) . EGFR/HER2-IN-4 shows potent EGFR kinase inhibitory activity against L858R and T790M mutations. EGFR/HER2-IN-4 exhibits significant anti-tumour effects in vivo and can be used to study lung cancer.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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