FGFR3-IN-2

2428742-58-7

Others, VEGFR, FGFR

Tyrosine Kinase/Adaptors, Angiogenesis, Others

FGFR3-IN-2 (compound 18b) is a potent and selective FGFR3 inhibitor, exhibiting inhibition with an IC50 of 4.1 nM for FGFR3 and 570 nM for VEGFR2.

O(CCN1CCOCC1)C2=C(C=CC(NC=3N=C(NC4=C(S(NCC)(=O)=O)C=CC=C4)N=CN3)=C2)N5CCN(C)CC5

C28H39N9O4S

597.73

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