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ATX inhibitor 13

Product Specifications

CAS Number

2485779-34-6

Target

Others, Apoptosis

Related Pathways

Others, Apoptosis

Bioactivity

ATX inhibitor 13 (compound 10c) is an orally active ATX inhibitor (IC50: 3.4 nM) that arrests the cell cycle of RAW264.7 cells in the G2 phase, inhibits cell proliferation and migration, induces apoptosis, and exhibits an inhibitory effect on tumour colony formation.

Smiles

N(C(OCC1=CC(Cl)=CC(Cl)=C1)=O)C=2N3C(=NC2CC)C(C)=CC(=C3)C4=CC=C(CN5CCN(CCO)CC5)C=C4

Molecular Formula

C31H35Cl2N5O3

Molecular Weight

596.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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