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EZH2-IN-9

Product Specifications

CAS Number

2700897-24-9

Target

Histone Methyltransferase, Others

Related Pathways

Chromatin/Epigenetic, Others

Bioactivity

EZH2-IN-9 is a potent inhibitor of EZH2, which, through overexpression or mutations in the SET region (Y641F, Y641N, A687V, A677G point mutations), causes abnormal elevations in H3K27me3 and contributes to the growth and development of various tumours (e.g., breast cancer, prostate cancer, leukaemia) . EZH2-IN-9 has shown potential for cancer research.

Smiles

CC1=C2C(OC(C)(O2)[C@@H]3CC[C@@H](C(=O)N4CC(F)(F)C4)CC3)=C(Cl)C=C1C(NCC5=C(SC)C=C(C)NC5=O)=O

Molecular Formula

C28H32ClF2N3O5S

Molecular Weight

596.09

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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