T-Type calcium channel inhibitor 2
Product Specifications
Target
Others, Calcium Channel
Related Pathways
Metabolism, Others, Membrane transporter/Ion channel
Bioactivity
T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, specifically acting on Cav3.1 (α1G) with an IC50 of 31.0 μM, Cav3.2 (α1H) with an IC50 of 83.1 μM, and Cav3.3 (α1I) (α1H) . T-Type calcium channel inhibitor 2 exhibited cytotoxicity against A549 and HCT-116 cells with IC50s of 5.0 μM and 6.4 μM, respectively.
Molecular Formula
C36H39FN4OS
Molecular Weight
594.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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