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T-Type calcium channel inhibitor 2

Product Specifications

Target

Others, Calcium Channel

Related Pathways

Metabolism, Others, Membrane transporter/Ion channel

Bioactivity

T-Type calcium channel inhibitor 2 (compound 6g) is a potent inhibitor of the T-type calcium channel, specifically acting on Cav3.1 (α1G) with an IC50 of 31.0 μM, Cav3.2 (α1H) with an IC50 of 83.1 μM, and Cav3.3 (α1I) (α1H) . T-Type calcium channel inhibitor 2 exhibited cytotoxicity against A549 and HCT-116 cells with IC50s of 5.0 μM and 6.4 μM, respectively.

Molecular Formula

C36H39FN4OS

Molecular Weight

594.78

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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