BMS-536924
Product Specifications
CAS Number
468740-43-4
Target
Apoptosis, MEK, FAK, IGF-1R, Src
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, MAPK, Cytoskeletal Signaling, Apoptosis
Purity
0.9919
Bioactivity
BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for Akt1, MAPK1/2.
Smiles
Cc1cc(cc2nc([nH]c12)-c1c(NC[C@@H](O)c2cccc(Cl)c2)cc[nH]c1=O)N1CCOCC1
Molecular Formula
C25H26ClN5O3
Molecular Weight
479.96
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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