PAIR2
Product Specifications
CAS Number
2771006-54-1
Target
Others, IRE1
Related Pathways
Cell Cycle/Checkpoint, Others
Bioactivity
PAIR2 is a potent, selective partial antagonist of IRE1α RNase, effectively occupying the ATP-binding site of IRE1α in cells. This action prevents a potent KIRA from inhibiting XBP1 splicing [1].
Smiles
O(C=1C2=C(C(NS(CC(F)(F)F)(=O)=O)=C(F)C1C)C=CC=C2)C3=C(C=CC=N3)C4=NC(N[C@H]5CCCNC5)=NC=C4
Molecular Formula
C27H26F4N6O3S
Molecular Weight
590.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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