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Vandetanib trifluoroacetate

Product Specifications

CAS Number

338992-53-3

Target

Others, Autophagy, Apoptosis, VEGFR

Related Pathways

Angiogenesis, Others, Tyrosine Kinase/Adaptors, Autophagy, Apoptosis

Bioactivity

Vandetanib trifluoroacetate (D6474 trifluoroacetate) is an orally active and potent VEGFR2/KDR tyrosine kinase inhibitor with an IC50 value of 40 nM. It also inhibits VEGFR3/FLT4 and EGFR/HER1, with IC50 values of 110 nM and 500 nM respectively.

Smiles

OC(=O)C(F)(F)F.COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1

Molecular Formula

C24H25BrF4N4O4

Molecular Weight

589.386

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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