Vandetanib trifluoroacetate
Product Specifications
CAS Number
338992-53-3
Target
Others, Autophagy, Apoptosis, VEGFR
Related Pathways
Angiogenesis, Others, Tyrosine Kinase/Adaptors, Autophagy, Apoptosis
Bioactivity
Vandetanib trifluoroacetate (D6474 trifluoroacetate) is an orally active and potent VEGFR2/KDR tyrosine kinase inhibitor with an IC50 value of 40 nM. It also inhibits VEGFR3/FLT4 and EGFR/HER1, with IC50 values of 110 nM and 500 nM respectively.
Smiles
OC(=O)C(F)(F)F.COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1
Molecular Formula
C24H25BrF4N4O4
Molecular Weight
589.386
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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