Cobimetinib hemifumarate
Product Specifications
CAS Number
1369665-02-0
Target
Others, Apoptosis, MEK
Related Pathways
MAPK, Others, Apoptosis
Bioactivity
Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1.
Smiles
OC(=O)\C=C\C(O)=O.OC1(CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)[C@@H]1CCCCN1.OC1(CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)[C@@H]1CCCCN1
Molecular Formula
C46H46F6I2N6O8
Molecular Weight
1178.707
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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