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Cobimetinib hemifumarate

Product Specifications

CAS Number

1369665-02-0

Target

Others, Apoptosis, MEK

Related Pathways

MAPK, Others, Apoptosis

Bioactivity

Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1.

Smiles

OC(=O)\C=C\C(O)=O.OC1(CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)[C@@H]1CCCCN1.OC1(CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F)[C@@H]1CCCCN1

Molecular Formula

C46H46F6I2N6O8

Molecular Weight

1178.707

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Frequently Asked Questions

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