LXR antagonist 2
Product Specifications
Target
Others
Related Pathways
Others
Bioactivity
LXR antagonist 2 (compound 10rr) is a potent LXR (liver X receptor) inverse agonist, targeting LXRβ (IC50: 0.36 μM) and LXRα (IC50: 2.25 μM) . It serves as an adipogenesis inhibitor, downregulating LXR target genes SREBP-1c, ACC, FAS, and SCD-1, and demonstrates hypolipidemic activity in Triton WR-1339-induced hyperlipidemic mice.
Molecular Formula
C34H40N2O5S
Molecular Weight
588.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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