Ifebemtinib
Product Specifications
CAS Number
1227948-82-4
Target
FAK
Related Pathways
Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Angiogenesis
Purity
0.9985
Bioactivity
Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule formation and in situ tumour growth in malignant pleural mesotheliomas, and may be useful for the study of breast and ovarian cancer.
Smiles
COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(c(Oc2cccc3CN(C)C(=O)c23)n1)C(F)(F)F
Molecular Formula
C28H28F4N6O4
Molecular Weight
588.55
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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