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Ifebemtinib

Product Specifications

CAS Number

1227948-82-4

Target

FAK

Related Pathways

Tyrosine Kinase/Adaptors, Cytoskeletal Signaling, Angiogenesis

Purity

0.9985

Bioactivity

Ifebemtinib (BI-853520) is an orally active and potent inhibitor of adhesion plaque kinase (FAK) (IC50=1 nM) with anti-tumour activity that inhibits globule formation and in situ tumour growth in malignant pleural mesotheliomas, and may be useful for the study of breast and ovarian cancer.

Smiles

COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(c(Oc2cccc3CN(C)C(=O)c23)n1)C(F)(F)F

Molecular Formula

C28H28F4N6O4

Molecular Weight

588.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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