ATX inhibitor 11
Product Specifications
CAS Number
2485779-27-7
Target
Others, PDE
Related Pathways
Others, Metabolism
Bioactivity
ATX inhibitor 11 is a potent inhibitor of ATX (autotaxin) (IC50: 2.7 nM) . ATX inhibitor 11 alleviates the severity of fibrotic tissue and effectively reduces the deposition of α-SMA, a biomarker of fibrosis, in a mouse model of fibrosis. ATX inhibitor 11 can be used to study lung fibrosis.
Smiles
N(C(OCC=1C=C2C(=CC1)OCO2)=O)C=3N4C(=NC3CC)C(C)=CC(=C4)C5=CC=C(C(=O)N6CCN(CCO)CC6)C=C5
Molecular Formula
C32H35N5O6
Molecular Weight
585.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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