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ATX inhibitor 11

Product Specifications

CAS Number

2485779-27-7

Target

Others, PDE

Related Pathways

Others, Metabolism

Bioactivity

ATX inhibitor 11 is a potent inhibitor of ATX (autotaxin) (IC50: 2.7 nM) . ATX inhibitor 11 alleviates the severity of fibrotic tissue and effectively reduces the deposition of α-SMA, a biomarker of fibrosis, in a mouse model of fibrosis. ATX inhibitor 11 can be used to study lung fibrosis.

Smiles

N(C(OCC=1C=C2C(=CC1)OCO2)=O)C=3N4C(=NC3CC)C(C)=CC(=C4)C5=CC=C(C(=O)N6CCN(CCO)CC6)C=C5

Molecular Formula

C32H35N5O6

Molecular Weight

585.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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