Laniquidar
Product Specifications
CAS Number
197509-46-9
Target
Others|||P-gp
Related Pathways
Membrane transporter/Ion channel|||Others|||Neuroscience
Bioactivity
Laniquidar (R101933) is a third generation non-competitive inhibitor of P-glycoprotein (P-gp) (IC50: 0.51 ?M) with limited oral bioavailability. It can also be used to modulate multidrug resistance transporters.
Smiles
C(OC)(=O)C=1N2C(C(C=3C(CC2)=CC=CC3)=C4CCN(CCC5=CC=C(OCC6=NC7=C(C=C6)C=CC=C7)C=C5)CC4)=NC1
Molecular Formula
C37H36N4O3
Molecular Weight
584.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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