B-Raf IN 5
Product Specifications
CAS Number
2648698-30-8
Target
Others, Raf
Related Pathways
MAPK, Others
Bioactivity
B-Raf IN 5 is a potent inhibitor of the protein kinase B-Raf (IC50: 2.0 nM) . B-Raf IN 5 resists rapid metabolism and does not bind to the secondary target PXR.
Smiles
FC1=C(C2=C(SC(=N2)C3COCCN3)C4=NC(N)=NC=C4)C=C(Cl)C=C1NS(=O)(=O)C5=C(F)C=CC(F)=C5
Molecular Formula
C23H18ClF3N6O3S2
Molecular Weight
583.01
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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