JAK2/FLT3-IN-1 TFA
Product Specifications
Target
Others, Apoptosis, FLT, JAK
Related Pathways
JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Apoptosis, Stem Cells, Others
Bioactivity
JAK2/FLT3-IN-1 (TFA) is an orally active dual inhibitor of JAK2 (IC50: 0.7 nM) and FLT3 (IC50: 4 nM) that demonstrates anticancer effects, also affecting JAK1 (IC50: 26 nM) and JAK3 (IC50: 39 nM) .
Molecular Formula
C27H35F4N7O3
Molecular Weight
581.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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