KRAS G12C inhibitor 43
Product Specifications
CAS Number
2648808-69-7
Target
Others, Kras, Ras
Related Pathways
MAPK, GPCR/G Protein, Others
Bioactivity
KRAS G12C inhibitor 43 is a potent inhibitor of KRAS G12C and inhibits the migration and proliferation of H358 cells (IC50: 0.001-1 μM μM), A549 cells (IC50>1 μM) and HCC cells (IC50>1 μM) .
Smiles
O(C[C@H]1N(C)CCC1)C=2N=C(C3=C(N=C(C=C3)C=4C5=C(C=C(OC)C4)C=CC=C5)N2)N6C[C@H](CC#N)N(C(C=C)=O)CC6
Molecular Formula
C33H35N7O3
Molecular Weight
577.68
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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