Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

(±)-10-Hydroxycamptothecin

Product Specifications

UNSPSC Description

(±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity.

Target Antigen

Topoisomerase

Type

Natural Products

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/__plusmn__-10-Hydroxycamptothecin.html

Purity

99.57

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1C(O)(CC)C2=C(CO1)C(N3CC4=CC5=CC(O)=CC=C5N=C4C3=C2)=O

Molecular Weight

364.35

References & Citations

[1]Liu SY, et al. Interaction of several nucleoside triphosphate analogues and 10-hydroxycamptothecin with human DNA topoisomerases. Cancer Res. 1989 Mar 15;49(6):1366-70.|[2]Ping YH, et al. Anticancer effects of low-dose 10-hydroxycamptothecin in human colon cancer. Oncol Rep. 2006 May;15(5):1273-9.|[3]Fan J, et al. Detection of apoptosis exposed to 10-hydroxycamptothecin in T24 human urinary bladder cancer cells. Zhonghua Wai Ke Za Zhi. 1999 Jan;37(1):57-9.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N0275/racemic-10-Hydroxycamptothecin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N0275/racemic-10-Hydroxycamptothecin-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

64439-81-2

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human ZNF354A Protein Lysate
MBS8430234-01 0.02 mg

Human ZNF354A Protein Lysate

Ask
View Details
Human ZNF354A Protein Lysate
MBS8430234-02 5x 0.02 mg

Human ZNF354A Protein Lysate

Ask
View Details
Rabbit anti-PDIA4/ERP72 Antibody, Affinity Purified
A305-265A-T 10 µg

Rabbit anti-PDIA4/ERP72 Antibody, Affinity Purified

Ask
View Details
Anti-Hu IgD PE
1P-142-T025 25 Tests

Anti-Hu IgD PE

Ask
View Details
Crybb1 (NM_012936) Rat Tagged Lenti ORF Clone
RR215410L3 10 µg

Crybb1 (NM_012936) Rat Tagged Lenti ORF Clone

Ask
View Details
Human pre-microRNA Expression Construct Lenti-miR-768
PMIRH768PA-1 Bacterial Streak

Human pre-microRNA Expression Construct Lenti-miR-768

Ask
View Details