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CSF1R-IN-3

Product Specifications

CAS Number

2760584-90-3

Target

C-Fms, CSF-1R

Related Pathways

Tyrosine Kinase/Adaptors

Purity

0.984

Bioactivity

CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM. CSF1R-IN-3 has anti-proliferative activity against colorectal cancer cells. CSF1R-IN-3 exhibits anti-tumour effects and immune enhancing effects by inhibiting the migration of macrophages and inducing the reprogramming of M2-type macrophages to M1-type macrophages, thus exhibited activity against colorectal cancer cells.

Smiles

CN1CCN(CC(=O)Nc2c(C)[nH]c(\C=C3/C(=O)Nc4cc(NC(=O)Nc5cc(on5)C(C)(C)C)ccc34)c2C)CC1

Molecular Formula

C30H38N8O4

Molecular Weight

574.67

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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