PLK1/BRD4-IN-1
Product Specifications
CAS Number
2412707-81-2
Target
Apoptosis, Androgen Receptor, c-Myc, Epigenetic Reader Domain, PLK, Others
Related Pathways
Cell Cycle/Checkpoint, Others, Endocrinology/Hormones, Apoptosis, Chromatin/Epigenetic
Bioactivity
PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM) that demonstrates significant anti-tumor efficacy in vivo.
Smiles
C(N1C=2C(N3C([C@H]1CC)=NN=C3C)=CN=C(NC4=C(OC)C=C(C(NC5CCN(C)CC5)=O)C=C4)N2)C6CCCCC6
Molecular Formula
C31H43N9O2
Molecular Weight
573.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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