ALK5-IN-9
Product Specifications
CAS Number
2489611-06-3
Target
Others, TGF-beta/Smad
Related Pathways
Stem Cells, Others
Bioactivity
ALK5-IN-9 is a potent, orally active inhibitor of TGFβRI (ALK5) . ALK5-IN-9 inhibits ALK5 autophosphorylation (IC50: 25 nM) and inhibits NIH3T3 cell activity (IC50: 74.6 nM) . ALK5-IN-9 has shown research potential in cancer diseases.
Smiles
O(C=1C(=NN(C1)C2CC2)C3CCOCC3)C=4C=C(NC5=CC(C(F)(F)F)=C(C=C5)N6CCN(CCO)CC6)N=CC4
Molecular Formula
C29H35F3N6O3
Molecular Weight
572.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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