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ALK5-IN-9

Product Specifications

CAS Number

2489611-06-3

Target

Others|||TGF-beta/Smad

Related Pathways

Stem Cells|||Others

Bioactivity

ALK5-IN-9 is a potent, orally active inhibitor of TGF?RI (ALK5) . ALK5-IN-9 inhibits ALK5 autophosphorylation (IC50: 25 nM) and inhibits NIH3T3 cell activity (IC50: 74.6 nM) . ALK5-IN-9 has shown research potential in cancer diseases.

Smiles

O(C=1C(=NN(C1)C2CC2)C3CCOCC3)C=4C=C(NC5=CC(C(F)(F)F)=C(C=C5)N6CCN(CCO)CC6)N=CC4

Molecular Formula

C29H35F3N6O3

Molecular Weight

572.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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