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RORγt agonist 3

Product Specifications

CAS Number

2664106-24-3

Target

Others, ROR

Related Pathways

Others, Metabolism

Bioactivity

RORγt agonist 3 is a potent agonist of RORγt that induces Th17 cell differentiation, increases levels of pro-inflammatory cytokines, and enhances lymphocyte cytotoxicity. Moreover, [it] blocks the production of regulatory T cells and suppresses the immune response.

Smiles

N(CC1CC1)(C2=CC(=CC(=C2)C3CC3)C4CC4)C5=CC=C(C(N[C@@H](CC#N)C6=CC=C(S(CC)(=O)=O)C=C6)=O)C=C5

Molecular Formula

C34H37N3O3S

Molecular Weight

567.74

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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