FGFR4-IN-6
Product Specifications
Target
FGFR, Others
Related Pathways
Others, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
FGFR4-IN-6 is a covalent, reversible FGFR4 inhibitor (IC50: 5.4 nM) that exhibits good oral pharmacokinetic properties. In a xenograft mouse model of the Hep3B2.1-7 HCC cell line, FGFR4-IN-6 was able to significantly induce tumour regression without significant toxicity.
Molecular Formula
C31H33N7O4
Molecular Weight
567.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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