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ABN401

Product Specifications

CAS Number

2242563-15-9

Target

Others|||Apoptosis|||c-Met/HGFR

Related Pathways

Others|||Tyrosine Kinase/Adaptors|||Apoptosis

Bioactivity

ABN401 is a potent, selective, ATP-competitive inhibitor of c-MET (IC50: 10 nM) . ABN401 exhibits cytotoxicity against MET-loving cancer cells. c-MET phosphorylation in tumour tissues is inhibited by ABN401. ABN401 can be used in anti-cancer studies.

Smiles

CN1CCN(Cc2ccc(cc2)-c2cnc(nc2)N2CCOC(Cn3nnc4ncc(nc34)-c3cnn(C)c3)C2)CC1

Molecular Formula

C29H34N12O

Molecular Weight

566.66

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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