Thi-DPPY
Product Specifications
CAS Number
2307699-34-7
Target
Others, JAK
Related Pathways
Chromatin/Epigenetic, Angiogenesis, Stem Cells, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
Thi-DPPY is a potent, orally active JAK3 inhibitor that acts on BTK (IC50: 62.4 nM), JAK (IC50: 1.38 nM) . Thi-DPPY is anti-proliferative against HBE cells. Thi-DPPY has anti-inflammatory effects in vivo. Thi-DPPY has shown research potential in idiopathic pulmonary fibrosis (IPF) .
Smiles
O(C1=C2C(=NC(NC3=CC(Cl)=C(OCCCN4CCOCC4)C=C3)=N1)C=CS2)C5=CC(NC(C=C)=O)=CC=C5
Molecular Formula
C28H28ClN5O4S
Molecular Weight
566.07
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx225284-01 50 µL
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody
Sign In for Pricing
View Details abx225284-02 100 µL
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody
Sign In for Pricing
View Details abx225284-03 200 µL
Mitochondrial Antiviral Signaling Protein (MAVS) Antibody
Sign In for Pricing
View Details 
RK10924 96 Tests
Human FUN14 domain-containing protein 2 (FUNDC2) ELISA Kit
Sign In for Pricing
View Details 
bs-24629R-APC-Cy5.5 100 µL
ERK5 Polyclonal Antibody, APC-Cy5.5 Conjugated
Sign In for Pricing
View Details