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MRTX-EX185

Product Specifications

Target

Ras|||Kras|||Others

Related Pathways

Others|||MAPK|||GPCR/G Protein

Bioactivity

MRTX-EX185 is an effective inhibitor of GDP-loaded KRAS and KRAS (G12D) with an IC50=90 nM for KRAS (G12D) . MRTX-EX185 is also capable of binding GDP-loaded HRAS.

Molecular Formula

C33H33FN6O2

Molecular Weight

564.65

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/8419A176-C879-4201-AF19-8DBD5DCDB105/T64000

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