MRTX-EX185
Product Specifications
Target
Ras, Kras, Others
Related Pathways
Others, MAPK, GPCR/G Protein
Bioactivity
MRTX-EX185 is an effective inhibitor of GDP-loaded KRAS and KRAS (G12D) with an IC50=90 nM for KRAS (G12D) . MRTX-EX185 is also capable of binding GDP-loaded HRAS.
Molecular Formula
C33H33FN6O2
Molecular Weight
564.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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