EGFR-IN-50
Product Specifications
CAS Number
2044508-48-5
Target
Others|||EGFR
Related Pathways
JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis
Bioactivity
EGFR-IN-50 is a potent EGFR inhibitor targeting L858R resistance mutations, acting on TEL-EGFR-L858R-BaF3 and TEL-EGFR-T790M-L858R-BaF3 with GI50 values of 8 nM and 6.03 ?M, respectively. EGFR-IN-50 exhibits anti-proliferative effects on cancer cells. .
Smiles
N(C=1C2=C(C=C(OCCCOC(CCSSCC=C)=O)C(OC)=C2)N=CN1)C3=CC(Br)=CC=C3
Molecular Formula
C24H26BrN3O4S2
Molecular Weight
564.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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