BRD4/CK2-IN-1
Product Specifications
CAS Number
2756851-99-5
Target
Apoptosis, Casein Kinase, Epigenetic Reader Domain, Autophagy
Related Pathways
Chromatin/Epigenetic, Metabolism, Autophagy, Stem Cells, Apoptosis
Purity
0.9902
Bioactivity
BRD4/CK2-IN-1 is a small molecule inhibitor targeting BRD4 and CK2, with an IC50 of 180nM for BRD4 and 230nM for CK2. It inhibits the proliferation of MDA-MB-231 and MDA-MB-468 cells, inducing apoptosis and autophagy-related cell death. It can be used in triple-negative breast cancer research.
Smiles
O=C1N=C(NC=2C=C(OC)C=C(OC)C12)C=3C=CC(OCC(=O)NC4=CC=C(C(Cl)=C4)N5CCN(C)CC5)=CC3
Molecular Formula
C29H30ClN5O5
Molecular Weight
564.03
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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